Ambitious goals laid out to keep global warming in check call for scientifically sound methods for achieving them. Reducing carbon dioxide in the atmosphere is at the core of climate policies but, though effective methods to achieve this are known, we are still far from a global political consensus on their implementation. This delay and uncertainties surrounding the climate system may require us to take CO2 from the atmosphere. A new project called UPTAKE, financed by the European Union as part of the Horizon program, aims to carry out a systemic and integrated appraisal of a large portfolio of carbon dioxide removal (CDR) methods and their interactions with decarbonization and sustainability strategies. Bocconi is taking part in this project with Valentina Bosetti, of the Department of Economics.